Charlotte, NORTH%20CAROLINA7 Active Studies

Multiple Myeloma Clinical Trials in Charlotte, NORTH%20CAROLINA

Find 7 actively recruiting multiple myeloma clinical trials in Charlotte, NORTH%20CAROLINA. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
1,116
Enrolling

Recruiting Multiple Myeloma Studies in Charlotte

RecruitingCharlotte, NORTH%20CAROLINANCT06615479

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple My...

440 participants
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
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RecruitingCharlotte, NORTH%20CAROLINANCT05730036

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

This study is researching an experimental drug called linvoseltamab, also called REGN5458. Linvoseltamab has previously been studied by itself (without other cancer drugs) in participants who had adv...

410 participants
Regeneron Pharmaceuticals
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RecruitingCharlotte, NORTH%20CAROLINANCT04822337

Study of Carfilzomib, Lenalidomide, Dexamethasone and Belantamab Mafodotin in Multiple Myeloma

This research study is being done to learn if the study drug belantamab mafodotin, in combination with other standard medications, can improve multiple myeloma. This study will also help determine wha...

70 participants
Wake Forest University Health Sciences
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RecruitingCharlotte, NORTH%20CAROLINANCT05014646

Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients

This phase II trial studies the effects of leflunomide in treating African-American and European-American patients with high-risk smoldering multiple myeloma. Leflunomide is used to decrease the body'...

56 participants
City of Hope Medical Center
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RecruitingCharlotte, NORTH%20CAROLINANCT05145400

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The stu...

50 participants
UNC Lineberger Comprehensive Cancer Center
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RecruitingCharlotte, NORTH%20CAROLINANCT06523621

Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel

This study is designed to evaluate if treatment with adjuvant nivolumab improves depth of response in patients with relapsed refractory multiple myeloma (RRMM) who achieve a less-than-ideal response t...

50 participants
Wake Forest University Health Sciences
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RecruitingCharlotte, NORTH%20CAROLINANCT06577025

A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma

The purpose of this study is to evaluate the rate of response (how effectively treatment is working) with signs of potential cure at 5 years after the start of induction treatment. This is defined as ...

40 participants
Janssen Research & Development, LLC
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About Multiple Myeloma Clinical Trials in Charlotte

Multiple myeloma is a cancer of plasma cells in the bone marrow that produce abnormal antibodies. It can cause bone damage, kidney problems, and immune deficiency. Treatments have advanced significantly with proteasome inhibitors, immunomodulatory drugs, and CAR-T cell therapy.

There are currently 7 multiple myeloma clinical trials recruiting participants in Charlotte, NORTH%20CAROLINA. These studies are seeking a combined 1,116 participants. Research is being sponsored by Juno Therapeutics, Inc., a Bristol-Myers Squibb Company, Regeneron Pharmaceuticals, Wake Forest University Health Sciences and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Myeloma Clinical Trials in Charlotte — FAQ

Are there multiple myeloma clinical trials in Charlotte?

Yes, there are 7 multiple myeloma clinical trials currently recruiting in Charlotte, NORTH%20CAROLINA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Charlotte?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Charlotte research site will contact you about next steps.

Are clinical trials in Charlotte free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Charlotte studies also compensate for your time and travel.

What multiple myeloma treatments are being tested?

The 7 active trials in Charlotte are testing new therapies including novel drugs, biologics, and treatment approaches for multiple myeloma.

Data updated March 2, 2026 from ClinicalTrials.gov